MovDisordV3, Main, Exploration, bibRecord, 004F36

Pallidotomy for Tremor

Identifieur interne : 004F36 ( Main/Exploration ); précédent : 004F35; suivant : 004F37

Pallidotomy for Tremor

Auteurs : Andres M. Lozano [Canada] ; Anthony E. Lang [Canada] ; William D. Hutchison [Canada]

Source :

Movement Disorders [ 0885-3185 ] ; 1998.

RBID : ISTEX:FB14715DDAE7F69C49561A4FE7974DF7928999B8

Descripteurs français

Pascal (Inist)
- Adulte, Chirurgie stéréotaxique, Electrocoagulation, Pallidotomie, Pallidum, Parkinson maladie, Pronostic, Traitement, Tremblement, Unilatéral.
Wicri :
- topic : Adulte.

English descriptors

KwdEn :
- Adult, Electrocoagulation, Globus Pallidus (surgery), Globus pallidus internus, Humans, Pallidotomy, Pallidum, Parkinson disease, Parkinson's disease, Prognosis, Stereotaxic surgery, Treatment, Tremor, Tremor (surgery), Unilateral.
MESH :
- surgery : Globus Pallidus, Tremor.
- Humans.

Abstract

We studied tremor‐related activity in globus pallidus internus (GPi) neurons and the effects of pallidotomy on tremor in patients with Parkinson's disease. By using micro‐electrode recording, we identified GPi neurons with rhythmic firing at the frequency of contralateral tremor. There was a strong correlation between the tremor‐related neuronal activity and limb tremor (r = 0.73). The majority of tremor‐related neurons were located in the ventral one half of the caudal GPi, the area that is the target for pallidotomy. We found that pallidotomy produced striking improvements in off‐period contralateral tremor. These effects were immediate and were maintained for ≥ 2 years. This benefit is obtained despite the progressive nature of the illness and the often reduced dose of medications after surgery.

Url:

https://api.istex.fr/document/FB14715DDAE7F69C49561A4FE7974DF7928999B8/fulltext/pdf

DOI: 10.1002/mds.870131319

Affiliations:

Le document en format XML

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<author><name sortKey="Lang, Anthony E" sort="Lang, Anthony E" uniqKey="Lang A" first="Anthony E." last="Lang">Anthony E. Lang</name>
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<author><name sortKey="Hutchison, William D" sort="Hutchison, William D" uniqKey="Hutchison W" first="William D." last="Hutchison">William D. Hutchison</name>
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<series><title level="j">Movement Disorders</title>
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<term>Globus pallidus internus</term>
<term>Humans</term>
<term>Pallidotomy</term>
<term>Pallidum</term>
<term>Parkinson disease</term>
<term>Parkinson's disease</term>
<term>Prognosis</term>
<term>Stereotaxic surgery</term>
<term>Treatment</term>
<term>Tremor</term>
<term>Tremor (surgery)</term>
<term>Unilateral</term>
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<term>Tremor</term>
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<term>Chirurgie stéréotaxique</term>
<term>Electrocoagulation</term>
<term>Pallidotomie</term>
<term>Pallidum</term>
<term>Parkinson maladie</term>
<term>Pronostic</term>
<term>Traitement</term>
<term>Tremblement</term>
<term>Unilatéral</term>
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<front><div type="abstract" xml:lang="en">We studied tremor‐related activity in globus pallidus internus (GPi) neurons and the effects of pallidotomy on tremor in patients with Parkinson's disease. By using micro‐electrode recording, we identified GPi neurons with rhythmic firing at the frequency of contralateral tremor. There was a strong correlation between the tremor‐related neuronal activity and limb tremor (r = 0.73). The majority of tremor‐related neurons were located in the ventral one half of the caudal GPi, the area that is the target for pallidotomy. We found that pallidotomy produced striking improvements in off‐period contralateral tremor. These effects were immediate and were maintained for ≥ 2 years. This benefit is obtained despite the progressive nature of the illness and the often reduced dose of medications after surgery.</div>
</front>
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Movement Disorders (revue)

Pallidotomy for Tremor

Pallidotomy for Tremor

Source :

Descripteurs français

English descriptors

Abstract

Links toward previous steps (curation, corpus...)

Le document en format XML

Pour manipuler ce document sous Unix (Dilib)

Pour mettre un lien sur cette page dans le réseau Wicri

	Movement Disorders (revue)
	Attention, ce site est en cours de développement ! Attention, site généré par des moyens informatiques à partir de corpus bruts. Les informations ne sont donc pas validées.